基本信息:
姓名:吴伟娜
性别:女
出生年月:1985.6. 19
最终学历(学位):博士研究生
职称:副教授
学术兼职:中国化学会高级会员,Sensors and Actuators B: Chemical、Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy、Journal of Molecular Structure、无机化学学报等学术期刊审稿人。
联系方式:wuwn08@hpu.edu.cn
●教育(工作)经历:(从本科写起,含在外进修、国外访学、工作等)
1999年9月-2003年6月,河南大学伟德betvlctor国际官网攻读本科,获学士学位;
2003年9月-2008年6月,兰州大学伟德betvlctor国际官网硕博连读;获无机化学博士学位;
2008年6月-至今, 伟德国际BETVlCTOR伟德betvlctor国际官网工作;
2019年2月-2020年6月,美国南佛罗里达大学访问学者
l教学情况:
主讲《有机化学》、《分析化学》《金属材料》《大学化学》(本科生)
参编教材:《化学反应原理及反应器研究》(副主编)
指导硕士10名。
l科研领域:
主要从事功能配合物、复合荧光探针等方面研究工作。
l科研成果:(包括项目、论文,成果,鉴定、专利、著作、在研课题等,主要的、有代表性的)
近五年主持国家自然科学基金青年基金1项、河南省重点研发与推广专项(科技攻关)1项,河南省高等学校重点科研项目(基础研究计划)1项,河南省博士后启动基金项目1项,河南省高等学校基本科研业务费项目1项,伟德国际BETVlCTOR“双一流”学科培育项目1项和企业委托横向项目2项。出版著作1部,授权国家发明专利9项,发表SCI收录论文40余篇。
1.国家自然科学基金项目,NIR-AIE@MOFs/Apt复合探针对癌胚抗原的特异性超灵敏荧光传感(21907023),主持,2020.1-2022.12
2.河南省科技厅科技攻关项目,基于MOFs复合探针的超灵敏光气荧光比色试纸的研发(232102320092),主持,2023.01-2024.04
3.伟德国际BETVlCTOR基本科研业务费专项项目,ZIF-90基复合荧光探针对线粒体ROS和ATP的“零窜扰”同步定量检测与实时成像分析(NSFRF230402),主持,2023.1-2025.12
4.伟德国际BETVlCTOR安全学科“双一流”创建工程项目,AIE @CuInS2-QDs复合探针对肼的近红外比率荧光传感(AQ20230754),主持,2023.1-2025.12
5.河南省高等学校重点科研项目计划,AIE活性荧光团@硅量子点水溶性复合材料的制备及其对肼的可视化多色荧光传感(19A150001),主持,2019.1-2020.12
代表论文:
1.Wei-Na Wu1,*, Yu-Fei Song1, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, Tony D. James*, Multifunctional 1,3-benzoxazole-merocyanine-based probe for the ratiometric fluorescence detection of pH/HSO3-/viscosity in mitochondria, Chemical Engineering Journal 464 (2023) 142553.
2.Shuang-Shuang Liu1, Wei-Na Wu1,*, Xiao-Lei Zhao, Yun-Chang Fan, Yuan Wang*, Zhi-Hong Xu*, A dual-emission fluorescence probe for the detection of viscosity and hydrazine in environmental and biological samples, Analytica Chimica Acta, 1245 (2023) 340867.
3.Jin-Long Yan1, Ling Zhang1, Wei-Na Wu*, Yuan Wang, Zhi-Hong Xu*, A novel AIRE-based fluorescent ratiometric probe with endoplasmic reticulum-targeting ability for detection of hypochlorite and bioimaging, Bioorganic Chemistry, 131 (2023) 106319.
4.Pan Liu, Wei-Na Wu*, Yuan Wang *, Yun-Chang Fan a, Zhi-Hong Xu*, A dual-ratiometric mitochondria-targeted fluorescent probe to detect hydrazine in soil samples and biological imaging, Journal of Hazardous Materials 440 (2022) 129713
5.Ling Zhang, Wei-Na Wu*, Xiao-Lei Zhao, Yun-Chang Fan, Yuan Wang*, Zhi-Hong Xu*, A coumarin/cyanoacetamide-derived lysosome-targeting probe for detecting bisulfite and viscosity changes in living cells and zebrafish, Dyes and Pigments 208 (2022) 110862
6.Ling Zhang, Xue-Feng Han, Wei-Na Wu*, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, A novel fluorescence aggregation-induced emission active chemosensor for sequential determination of Cu2+ and S2- in an almost neat aqueous solution, Microchemical Journal 183 (2022) 107974
7.Ling Zhang, Jin-Long Yan, Wei-Na Wu*, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, A “turn-on” chalcone-based probe for hydrogen sulfide and imaging applications in lysosomes of living cells and zebrafish, Microchemical Journal 183 (2022) 107941
8.Yu-Fei Song, Wei-Na Wu*, Yuan Wang*, Xiao-Lei Zhao, Yun-Chang Fan, Zhi-Hong Xu*, Europium (III) complex-based fluorescent probe for instantaneous, selective, and sensitive detection of phosgene, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 280 (2022) 121553
9.Yu-Fei Song, Wei-Na Wu*, Xiao-Lei Zhao a, Yuan Wang*, Yun-Chang Fan, Xi-Yan Dong, Zhi-Hong Xu*, A simple colorimetric and fluorometric probe for rapid detection of CN– with large emission shift, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 280 (2022) 121540
10.Shuang-Shuang Liu1, Jin-Long Yan1, Wei-Na Wu*, Xiao-Lei Zhao, Yun-Chang Fan, Yuan Wang*, Zhi-Hong Xu*, Highly selective fluorescent probe for rapid turn-on detection and cell imaging of hypochlorite anion, Journal of Photochemistry & Photobiology, A: Chemistry 432 (2022) 114082
11.Xiao-Hong Li1, Xue-Feng Han1, Wei-Na Wu*, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, Simultaneous detection of lysosomal SO2 and viscosity using a hemicyanine-based fluorescent probe, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 280 (2022) 121519
12.Xiao-Hong Li1, Jin-Long Yan1, Wei-Na Wu*, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, A dual-response fluorescent probe for SO2 and viscosity and imaging application in lysosomes and zebrafish, Microchemical Journal 181 (2022) 107653.
13.Ling Zhang1, Jin-Long Yan1, Yuan Wang*, Xiao-Lei Zhao, Wei-Na Wu*, Yun-Chang Fan, Zhi-Hong Xu*, Ling-Ling Yan, A novel indene-chalcone-based fluorescence probe with lysosometargeting for detection of endogenous carboxylesterases and bioimaging, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 278 (2022) 121329
14.Xiao-Hong Li1, Xue-Feng Han1, Wei-Na Wu*, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, A quinoline-based probe for the ratiometric fluorescent detection of sulfite in lysosomes of living cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 275 (2022) 121160
15.Fang-Fang Guo1, Wei-Na Wu1, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Chuan-Xiang Zhang*, Zhi-Hong Xu*, A water-soluble lysosome-targetable fluorescent probe for carboxylesterase detection and its application in biological imaging, Dyes and Pigments 199 (2022) 110079
16.Xiao-Chuang Chang1, Xue-Feng Han1, Bing-Jie Liu , Zi-Yi Jiang, Shuai-Ze Li, Yue-Ming Lv, Ao-Long Li, Yuan Wang*, Wei-Na Wu*, A tosylhydrazone-based probe for the ratiometric fluorescent detection of hypochlorite in endoplasmic reticulum of living cells. Journal of Molecular Structure 1255 (2022) 132382.
17.Fang-Fang Guo1, Xue-Feng Han1, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Wei-Na Wu*, Zhi-Hong Xu*, A ratiometric fluorescent probe for hydrogen sulfide in neat aqueous solution and its application in lysosome-targetable cell imaging, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 270 (2022) 120835
18.Xiao-Hong Li1, Xue-Feng Han1, Wei-Na Wu*, Yuan Wang*, Yun-Chang Fan , Xiao-Lei Zhao , Zhi-Hong Xu*, Simple thiosemicarbazone "switch" sensing of Hg2+ and biothiols in pure aqueous solutions and application to imaging in lysosomes, Journal of Molecular Structure 1250 (2022) 131811
19.Fang-Fang Guo, Bei-Bei Wang, Wei-Na Wu, Wen-Yan Bi*, Zhi-Hong Xu*, Yun-Chang Fan, Lin-Yan Bian, Yuan Wang*, A pyrazine-containing hydrazone derivative for sequential detection of Al3+ and F−,Journal of Molecular Structure 1251 (2022) 132073.
20.Yu-Fei Song1, Hong-Xin Cai1, Wei-Na Wu*, Hai-Tao Zong, Ming Li, Yuan Wang*, Yun-Chang Fan, Zhi-Hong Xu*, A simple hydrazone probe for recognition of Al3+ and PPi and its applicability in lysosomal imaging, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 268 (2022) 120680
21.Xiao-Hong Li1, Jin-Long Yan1, Hai-Tao Zong , Wei-Na Wu*, Yuan Wang , Xiao-Lei Zhao, Yun-Chang Fan, Zhi-Hong Xu*, A 1,8-naphthalimide-based turn-on fluorescent probe for imaging Cu2+ in lysosomes, Inorganic Chemistry Communications 134 (2021) 109026
22.Pan Liu1 , Xue-Feng Han1, Wei-Na Wu*, Yuan Wang*, Yun-Chang Fan , Xiao-Lei Zhao, Zhi-Hong Xu*, A water soluble hydrazone probe for subsequent fluorescent detection of Zn2+ and S2− in neat aqueous solution and imaging in mitochondria of living cells, Journal of Molecular Structure 1249 (2022) 131629.
23.Mu-Xuan Lv, Lin-Yan Bian*, Wei-Na Wu*, Zhi-Hong Xu*, Yuan Wang, Xiao-Lei Zhao, Zhou-Qing Xu, Yun-Chang Fan, Ling-Ling Yan, Thiocarbazone-appended coumarin: An easily accessible ratiometric fluorescent chemosensor for multianalyte (Zn2+ and Cu2+) systems, Coloration Technology.138 (2022) 157–167.
24.Fang-Fang Guo1, Wei-Na Wu1, Xiao-Lei Zhao, Yuan Wang*, Yun-Chang Fan, Chuan-Xiang Zhang*, Zhi-Hong Xu*, A deep-red lysosome-targetable fluorescent probe for detection of hypochlorous acid in pure water and its imaging application in living cells and zebrafish, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 264 (2022) 120270
著作
1.吴伟娜等,有机化学反应原理,化学工业出版社,2013
专利
1.吴伟娜,王元,陈兴颖,陈泽华,李慧军,徐周庆,吴浩, 一种基于萘酰亚胺衍生物的比色探针及其制备方法与应用, 2016108716023,国家发明专利,2018.10.16。
2.吴伟娜,王元,陈兴颖,陈泽华,李慧军,徐周庆,吴浩,一种基于喹啉酰腙衍生物的荧光探针及其制备方法与应用,2016108983575,国家发明专利,2019.2.1。
3.吴伟娜,王元,李慧军,蔡红新,闫玲玲,一种罗丹明B衍生物、制备方法及其作为荧光探针的应用,2015109637645,国家发明专利,2019.2.1。
4.吴伟娜,王元,陈兴颖,陈泽华,李慧军,徐周庆,吴浩,一种基于吡咯双腙的荧光探针及其制备方法与应用,201610874537X,国家发明专利,2019.2.19。
5.吴伟娜,王元,陈亮,蔡红新,吴浩, 一种基于喹啉衍生物的荧光探针及其制备方法和应用,2017109276167,国家发明专利, 2020.12.3.
6.吴伟娜,王元,赵晓雷,郭芳芳,李晓红,刘盼,一种吡啶-香豆素衍生物荧光探针及其制备方法和应用,2019111560531,国家发明专利,2021.5.4
7.吴伟娜,王元,郭芳芳,宋雨飞,刘爽爽,色烯-吡啶衍生物荧光探针、制备方法及应用,2020114844449,国家发明专利,2022.2.1.
8.吴伟娜,王元,赵晓雷,张玲,宋雨飞,刘爽爽,一种萘并吡喃醛衍生物及其制备方法和应用,202010871803X,国家发明专利,2022.07.05
9.吴伟娜,王元,赵晓雷,刘盼,郭芳芳,李晓红,一种吡咯-萘酰亚胺衍生物荧光探针及其制备方法和应用,2019 1 11571273,国家发明专利,2023.2.7.